No matter the need for new and advanced Fuze technology, the US military will not accept a fuze design if it is not safe to manufacture, test, store, transport, handle, and deploy. As such, a myriad of safety requirements and analysis must be met. MIL-STD 1316, MIL-STD-1901, are just a few defined design standards. In addition, extensive analysis and physical testing are required. The Army Fuze Safety Review Board (AFSRB) is the principal gateway to fielding new fuze technology and is responsible for ensuring the Army's safety requirements are met. This paper will focus on proving that safe separation requirements are met. This involves extensive analysis that predict both reliability and explore all possible failure mechanisms.